Our new research article: “GutAlive® enables DNA-based microbiome analysis without disrupting the original composition and diversity”

A precise faecal microbiome analysis requires normalized methods for microbiome sampling, transport and manipulation in order to obtain a representative snapshot of the microbial community. That is why Microviable Therapeutics SL developed GutAlive®, the unique stool collection kit that generates an anaerobic atmosphere enabling oxygen-sensitive bacteria to survive, maintaining the original microbiome composition and diversity.

In this research paper, we demonstrate that GutAlive maintains the viability of bacterial cells for up to 5 days, at room temperature, preserving the integrity of the DNA as well, without the addition of undesired reagents that directly interact with the sample. This commercial device enables self-collection of the sample by the donor, and the shipment to the laboratory facilities for microbiome metagenomic analysis, faecal microbiota transplantation and bacterial isolation, among other downstream applications.

Download the complete article here